Categories: Pathology

Thyroid Tests Interpretation

Thyroid Tests Interpretation (TSH, T3, T4, rT3, Thyroid Antibodies)

High
Low
TSH
(Thyroid Stimulating Hormone)
  • Hashimoto’s Thyroiditis
  • Iodine deficiency
  • Large doses of iodine
  • Goitrogenic foods
  • Excessive stress and cortisol
  • Obesity
  • Thyroiditis
  • Severe and chronic illness
  • Pituitary tumour
  • Medications:
    • Antithyroid medications
    • Lithium
    • Potassium iodide
  • Graves disease
  • Pituitary dysfunction
  • Certain tumours
  • Severe illness
  • Medications:
    • Aspirin
    • Dopamine
    • Heparin
    • Steroids
    • Levothyroxine
T4
(Thyroxine)
  • Graves disease
  • Pregnancy
  • Hepatitis
  • Thyroid cancer
  • Acute thyroiditis
  • Toxic thyroid nodule
  • Medications:
    • Aspirin
    • Danazol
    • Heparin
    • Clofibrate
    • Oestrogens
    • Heroin
    • Oral contraceptives
    • Levothyroxine
  • Hashimoto’s thyroiditis
  • Nutritional deficiency:
    • Iodine
    • Iron
    • Selenium
    • Tyrosine
  • Renal failure
  • Cushings syndrome
  • Cirrhosis
  • Mediations:
    • Furosemide
    • Methadone
    • Phenytoins
    • Rifampicin
    • Anabolic steroids
    • Androgens
    • Antithyroid drugs
    • Lithium
    • Phenytoin
    • T3 medication
T3
(Triiodothyronine)
  • Graves disease
  • Pregnancy
  • Hepatitis
  • Thyroid cancer
  • Acute thyroiditis
  • Toxic thyroid nodule
  • Medications:
    • Oestrogens
    • Methodone
    • Oral contraceptives
  • Hashimoto’s thyroiditis
  • Nutritional deficiency:
    • Iodine
    • Iron
    • Selenium
    • Tyrosine
  • Inflammation
  • Stress
  • Obesity
  • Renal failure
  • Cushings syndrome
  • Cirrhosis
  • Liver diseases
  • Mediations:
    • Anabolic steroids
    • Androgens
    • Lithium
    • Phenytoin
    • Propranolol
    • Salicylates (high dose)
    • Reserpine
rT3
(Reverse Triiodothyronine)
  • Stress
  • Inflammation
  • Elevated cortisol
  • Trauma
  • Anorexia nervosa
  • Hepatic dysfunction
  • Iron deficiency
Antithyroid peroxidase Antibody
(Anti-TPO, TPO-Ab, Thyroid Autoantibody)
  • Hashimotos thyroiditis
  • Graves disease
  • Rheumatoid arthritis
  • Rheumatoid-collagen disease
  • Pernicious anaemia
  • Thyroid cancer
Antithyroglobulin Antibody
(Thyroid Autoantibody)
  • Hashimotos thyroiditis
  • Graves disease
  • Rheumatoid arthritis
  • Rheumatoid-collagen disease
  • Pernicious anaemia
  • Thyroid cancer
TBG
(Thyroid Binding Globulin)
  • Pregnancy
  • Oral contraceptives
  • Oestrogen replacement therapy
  • Oestrogen producing tumours
  • Infectious hepatitis
  • Hypoproteinaemia
    • Malnutrition
    • Malabsorption
  • Ovarian failure
  • Testosterone producing tumours
  • Excessive stress
Pagana, K. D., & Pagana, T. J. (2019). Mosby’s Diagnostic and Laboratory Test Reference (14th ed.) Elsevier Health Sciences
Williamson, M. A., Snyder, L. M., & Wallach, J. B. 1. (2011). Wallach’s interpretation of diagnostic tests. (9th ed.) Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins.
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NHC
3 years ago

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