Categories: Pathology

Iron Studies Interpretation​

Iron Studies Interpretation

High
Low
Serum Iron
  • Haemochromatosis
  • Haemosiderosis
  • Haemolytic anaemia
  • Hepatitis
  • Hepatic necrosis
  • Lead toxicity
  • Iron poisoning
  • Blood transfusion
  • Insufficient dietary intake of iron
  • Chronic blood loss
  • Malabsorption
  • Pregnancy (later stages)
  • Iron deficiency anaemia
  • Neoplasia
  • Heavy menstrual flow
TIBC/Transferrin
  • Oral contraceptives
  • Pregnancy (later stages)
  • Polycythaemia vera
  • Iron deficiency anaemia
  • Hypoproteinaemia
  • Inflammatory diseases
  • Cirrhosis
  • Haemolytic anaemia
  • Pernicious anaemia
  • Sickle cell anaemia
Transferrin Saturation
  • Haemochromatosis
  • Haemosiderosis
  • Acute iron overdose
  • Haemolytic anaemia
  • Iron deficiency anaemia
  • Chronic illness
Ferritin
  • Haemochromatosis
  • Haemosiderosis
  • Megaloblastic anemia
  • Haemolytic anemia
  • Inflammatory conditions
  • Alcoholic or inflammatory liver disease
  • Advanced cancers
  • Chronic illnesses (e.g., leukemias, cirrhosis, chronic hepatitis)
  • Collagen vascular diseases
  • Haemophagocytic syndromes
  • Sideroblastic anaemia
  • Iron deficiency anaemia
  • Severe protein deficiency
  • Haemodialysis



Disease
Iron
TIBC/Transferrin
UIBC
% Transferrin Saturation
Ferritin
Iron Deficiency
Low
High
High
Low
Low
Haemochromatosis/Haemosiderosis
High
Low
Low
High
High
Chronic Illness
Low
Normal/Low
Normal/Low
Normal/Low
Normal/High
Haemolytic Anaemia
High
Normal/Low
Normal/Low
High
High
Sideroblastic Anaemia
Normal/High
Normal/Low
Normal/Low
High
High
Iron Poisoning
High
Normal
Low
High
Normal
Hechtman, L. (2018). Clinical Naturopathic Medicine. Elsevier Health Sciences.
Pagana, K. D., & Pagana, T. J. (2019). Mosby’s Diagnostic and Laboratory Test Reference (14th ed.) Elsevier Health Sciences
Williamson, M. A., Snyder, L. M., & Wallach, J. B. 1. (2011). Wallach’s interpretation of diagnostic tests. (9th ed.) Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins.
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